Selection, Characterization and Application of Artificial DNA Aptamer Containing Appended Bases with Sub-nanomolar Affinity for a Salivary Biomarker

We have attained a chemically modified DNA aptamer against salivary α-amylase (sAA), which attracts researchers’ attention as a useful biomarker for assessing human psychobiological and social behavioural processes, although high affinity aptamers have not been isolated from a random natural DNA lib...

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Detalles Bibliográficos
Autores principales: Minagawa, Hirotaka, Onodera, Kentaro, Fujita, Hiroto, Sakamoto, Taiichi, Akitomi, Joe, Kaneko, Naoto, Shiratori, Ikuo, Kuwahara, Masayasu, Horii, Katsunori, Waga, Iwao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335659/
https://www.ncbi.nlm.nih.gov/pubmed/28256555
http://dx.doi.org/10.1038/srep42716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335659/
https://www.ncbi.nlm.nih.gov/pubmed/28256555
http://dx.doi.org/10.1038/srep42716

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