Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

Fibroblast growth factor 21 (FGF21) has emerged as an important beneficial regulator of glucose and lipid homeostasis but its levels are also abnormally increased in insulin-resistant states in rodents and humans. The synthetic retinoid Fenretinide inhibits obesity and improves glucose homeostasis i...

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Detalles Bibliográficos
Autores principales: Morrice, Nicola, Mcilroy, George D., Tammireddy, Seshu R., Reekie, Jennifer, Shearer, Kirsty D., Doherty, Mary K., Delibegović, Mirela, Whitfield, Phillip D., Mody, Nimesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335663/
https://www.ncbi.nlm.nih.gov/pubmed/28256636
http://dx.doi.org/10.1038/srep43782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335663/
https://www.ncbi.nlm.nih.gov/pubmed/28256636
http://dx.doi.org/10.1038/srep43782

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