Autophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death

Autophagy is a fundamental cellular homeostatic mechanism, whereby cells autodigest parts of their cytoplasm for removal or turnover. Neurodegenerative disorders are associated with autophagy dysregulation, and drugs modulating autophagy have been successful in several animal models. Microglial cell...

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Detalles Bibliográficos
Autores principales: Bussi, Claudio, Ramos, Javier Maria Peralta, Arroyo, Daniela S., Gaviglio, Emilia A., Gallea, Jose Ignacio, Wang, Ji Ming, Celej, Maria Soledad, Iribarren, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335665/
https://www.ncbi.nlm.nih.gov/pubmed/28256519
http://dx.doi.org/10.1038/srep43153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335665/
https://www.ncbi.nlm.nih.gov/pubmed/28256519
http://dx.doi.org/10.1038/srep43153

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