Cargando…

Autophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death

Autophagy is a fundamental cellular homeostatic mechanism, whereby cells autodigest parts of their cytoplasm for removal or turnover. Neurodegenerative disorders are associated with autophagy dysregulation, and drugs modulating autophagy have been successful in several animal models. Microglial cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bussi, Claudio, Ramos, Javier Maria Peralta, Arroyo, Daniela S., Gaviglio, Emilia A., Gallea, Jose Ignacio, Wang, Ji Ming, Celej, Maria Soledad, Iribarren, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335665/ https://www.ncbi.nlm.nih.gov/pubmed/28256519 http://dx.doi.org/10.1038/srep43153

Ejemplares similares

Type I IFNs Are Required to Promote Central Nervous System Immune Surveillance through the Recruitment of Inflammatory Monocytes upon Systemic Inflammation
por: Peralta Ramos, Javier María, et al.
Publicado: (2017)

Phosphatidyl-Inositol-3 Kinase Inhibitors Regulate Peptidoglycan-Induced Myeloid Leukocyte Recruitment, Inflammation, and Neurotoxicity in Mouse Brain
por: Arroyo, Daniela S., et al.
Publicado: (2018)

Effects of ginsenoside Re on LPS-induced inflammatory mediators in BV2 microglial cells
por: Lee, Kang-Woo, et al.
Publicado: (2012)

PACAP and VIP Modulate LPS-Induced Microglial Activation and Trigger Distinct Phenotypic Changes in Murine BV2 Microglial Cells
por: Karunia, Jocelyn, et al.
Publicado: (2021)

Ibrutinib suppresses LPS-induced neuroinflammatory responses in BV2 microglial cells and wild-type mice
por: Nam, Hye Yeon, et al.
Publicado: (2018)

Hydroxytyrosol Decreases LPS- and α-Synuclein-Induced Microglial Activation In Vitro
por: Gallardo-Fernández, Marta, et al.
Publicado: (2019)

Scoparone Inhibits LPS-Simulated Inflammatory Response by Suppressing IRF3 and ERK in BV-2 Microglial Cells
por: Cho, Duk-Yeon, et al.
Publicado: (2016)

LPS-Induced proNGF Synthesis and Release in the N9 and BV2 Microglial Cells: A New Pathway Underling Microglial Toxicity in Neuroinflammation
por: Duan, Li, et al.
Publicado: (2013)

Salidroside Reduces Cell Mobility via NF-κB and MAPK Signaling in LPS-Induced BV2 Microglial Cells
por: Hu, Haixia, et al.
Publicado: (2014)

Hypoxia potentiates cytotoxicity of LPS-activated microglial BV2 cells in vitro by synergistic effects on cytokine and nitric oxide secretion
por: Jung, Susan, et al.
Publicado: (2015)

Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice
por: Yan, Aijuan, et al.
Publicado: (2019)

Hispidin inhibits LPS-induced nitric oxide production in BV-2 microglial cells via ROS-dependent MAPK signaling
por: Jin, Mei-Hua, et al.
Publicado: (2021)

Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells
por: Juknat, Ana, et al.
Publicado: (2013)

Tryptanthrin Suppresses the Activation of the LPS-Treated BV2 Microglial Cell Line via Nrf2/HO-1 Antioxidant Signaling
por: Kwon, Young-Won, et al.
Publicado: (2017)

Involvement of NFƙB and MAPK signaling pathways in the preventive effects of Ganoderma lucidum on the inflammation of BV-2 microglial cells induced by LPS
por: Hilliard, Aaron, et al.
Publicado: (2020)

Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS
por: Wang, Li-Yu, et al.
Publicado: (2019)

Suppression of LPS-Induced Inflammation and Cell Migration by Azelastine through Inhibition of JNK/NF-κB Pathway in BV2 Microglial Cells
por: Nguyen, Phuong Linh, et al.
Publicado: (2021)

Effects of α-lipoic acid on LPS-induced neuroinflammation and NLRP3 inflammasome activation through the regulation of BV-2 microglial cells activation
por: Kim, Su Min, et al.
Publicado: (2019)

Investigations into the Role of Metabolism in the Inflammatory Response of BV2 Microglial Cells
por: Maher, Pamela
Publicado: (2021)

Trimethyltin-Induced Microglial Activation via NADPH Oxidase and MAPKs Pathway in BV-2 Microglial Cells
por: Kim, Da Jung, et al.
Publicado: (2015)

Minocycline inhibition of microglial rescues nigrostriatal dopaminergic neurodegeneration caused by mutant alpha-synuclein overexpression
por: Wang, Yong, et al.
Publicado: (2020)

Cell damage produced by magnetic fluid hyperthermia on microglial BV2 cells
por: Calatayud, M. Pilar, et al.
Publicado: (2017)

Aluminum-Induced Alterations in Purinergic System Parameters of BV-2 Brain Microglial Cells
por: Assmann, Charles Elias, et al.
Publicado: (2021)

RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells
por: Jung, Kyoung Hwa, et al.
Publicado: (2015)

The TSPO Ligands 2-Cl-MGV-1, MGV-1, and PK11195 Differentially Suppress the Inflammatory Response of BV-2 Microglial Cell to LPS
por: Azrad, Maya, et al.
Publicado: (2019)

Antineuroinflammatory Effect of Amburana cearensis and Its Molecules Coumarin and Amburoside A by Inhibiting the MAPK Signaling Pathway in LPS-Activated BV-2 Microglial Cells
por: de Araújo, Ana Bruna, et al.
Publicado: (2022)

Assessing the Anti-Inflammatory Activity of the Anxiolytic Drug Buspirone Using CRISPR-Cas9 Gene Editing in LPS-Stimulated BV-2 Microglial Cells
por: Thomas Broome, Sarah, et al.
Publicado: (2021)

Antioxidant and Anti-Inflammatory Mechanisms of Cardamonin through Nrf2 Activation and NF-kB Suppression in LPS-Activated BV-2 Microglial Cells
por: Barber, Kimberly, et al.
Publicado: (2023)

Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells
por: Choi, Yung Hyun, et al.
Publicado: (2012)

Effect of Glycine on BV-2 Microglial Cells Treated with Interferon-γ and Lipopolysaccharide
por: Egger, Florentina, et al.
Publicado: (2020)

Effects of Haloperidol, Risperidone, and Aripiprazole on the Immunometabolic Properties of BV-2 Microglial Cells
por: Racki, Valentino, et al.
Publicado: (2021)

PACAP and VIP Mitigate Rotenone-Induced Inflammation in BV-2 Microglial Cells
por: Broome, Sarah Thomas, et al.
Publicado: (2022)

Necrotic-like BV-2 microglial cell death due to methylmercury exposure
por: Martins, B., et al.
Publicado: (2022)

Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways
por: Ismail, Elysha Nur, et al.
Publicado: (2020)

3,4,5-Trihydroxycinnamic Acid Inhibits LPS-Induced iNOS Expression by Suppressing NF-κB Activation in BV2 Microglial Cells
por: Lee, Jae-Won, et al.
Publicado: (2012)

Royal Jelly Attenuates LPS-Induced Inflammation in BV-2 Microglial Cells through Modulating NF-κB and p38/JNK Signaling Pathways
por: You, Meng-Meng, et al.
Publicado: (2018)

Aspirin-triggered lipoxin A(4 )attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells
por: Wang, Yan-Ping, et al.
Publicado: (2011)

Curcumin alleviates LPS-induced inflammation and oxidative stress in mouse microglial BV2 cells by targeting miR-137-3p/NeuroD1
por: Gao, Feng, et al.
Publicado: (2019)

Long Noncoding RNA Expression Profile in BV2 Microglial Cells Exposed to Lipopolysaccharide
por: Li, Yajuan, et al.
Publicado: (2019)

The inhibitory effects of Orengedokuto on inducible PGE2 production in BV-2 microglial cells
por: Iwata, Yoshika, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_73c1tll9uv6gg8qm122hqpujfc