Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice

High-fat diets (HFD) are thought to contribute to the development of metabolism-related diseases. The long-term impact of HFD may be mediated by epigenetic mechanisms, and indeed, HFD has been reported to induce DNA methylation changes in white adipose tissue (WAT) near metabolism related genes. How...

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Detalles Bibliográficos
Autores principales: Zwamborn, Ramona A. J., Slieker, Roderick C., Mulder, Petra C. A., Zoetemelk, Inge, Verschuren, Lars, Suchiman, H. Eka D., Toet, Karin H., Droog, Simone, Slagboom, P. Eline, Kooistra, Teake, Kleemann, Robert, Heijmans, Bastiaan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335669/
https://www.ncbi.nlm.nih.gov/pubmed/28256596
http://dx.doi.org/10.1038/srep43261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335669/
https://www.ncbi.nlm.nih.gov/pubmed/28256596
http://dx.doi.org/10.1038/srep43261

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