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Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice
High-fat diets (HFD) are thought to contribute to the development of metabolism-related diseases. The long-term impact of HFD may be mediated by epigenetic mechanisms, and indeed, HFD has been reported to induce DNA methylation changes in white adipose tissue (WAT) near metabolism related genes. How...
Autores principales: | Zwamborn, Ramona A. J., Slieker, Roderick C., Mulder, Petra C. A., Zoetemelk, Inge, Verschuren, Lars, Suchiman, H. Eka D., Toet, Karin H., Droog, Simone, Slagboom, P. Eline, Kooistra, Teake, Kleemann, Robert, Heijmans, Bastiaan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335669/ https://www.ncbi.nlm.nih.gov/pubmed/28256596 http://dx.doi.org/10.1038/srep43261 |
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