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Myofibroblast differentiation and its functional properties are inhibited by nicotine and e-cigarette via mitochondrial OXPHOS complex III

Nicotine is the major stimulant in tobacco products including e-cigarettes. Fibroblast to myofibroblast differentiation is a key process during wound healing and is dysregulated in lung diseases. The role of nicotine and e-cigarette derived nicotine on cellular functions including profibrotic respon...

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Detalles Bibliográficos
Autores principales: Lei, Wei, Lerner, Chad, Sundar, Isaac K., Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335673/
https://www.ncbi.nlm.nih.gov/pubmed/28256533
http://dx.doi.org/10.1038/srep43213