The Expanding Family of Natural Anion Channelrhodopsins Reveals Large Variations in Kinetics, Conductance, and Spectral Sensitivity

Natural anion channelrhodopsins (ACRs) discovered in the cryptophyte alga Guillardia theta generate large hyperpolarizing currents at membrane potentials above the Nernst equilibrium potential for Cl(−) and thus can be used as efficient inhibitory tools for optogenetics. We have identified and chara...

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Detalles Bibliográficos
Autores principales: Govorunova, Elena G., Sineshchekov, Oleg A., Rodarte, Elsa M., Janz, Roger, Morelle, Olivier, Melkonian, Michael, Wong, Gane K.-S., Spudich, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335703/
https://www.ncbi.nlm.nih.gov/pubmed/28256618
http://dx.doi.org/10.1038/srep43358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335703/
https://www.ncbi.nlm.nih.gov/pubmed/28256618
http://dx.doi.org/10.1038/srep43358

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