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Antimicrobial efficacy against Pseudomonas aeruginosa biofilm formation in a three-dimensional lung epithelial model and the influence of fetal bovine serum

In vitro models that mimic in vivo host-pathogen interactions are needed to evaluate candidate drugs that inhibit bacterial virulence traits. We established a new approach to study Pseudomonas aeruginosa biofilm susceptibility on biotic surfaces, using a three-dimensional (3-D) lung epithelial cell...

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Detalles Bibliográficos
Autores principales: Crabbé, Aurélie, Liu, Yulong, Matthijs, Nele, Rigole, Petra, De La Fuente-Nùñez, César, Davis, Richard, Ledesma, Maria A., Sarker, Shameema, Van Houdt, Rob, Hancock, Robert E. W., Coenye, Tom, Nickerson, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335707/
https://www.ncbi.nlm.nih.gov/pubmed/28256611
http://dx.doi.org/10.1038/srep43321