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The intranasal adjuvant Endocine™ enhances both systemic and mucosal immune responses in aged mice immunized with influenza antigen

Despite availability of annual influenza vaccines, influenza causes significant morbidity and mortality in the elderly. This is at least in part a result of immunosenescence; the age-dependent decrease in immunological competence that results in greater susceptibility to infections and reduced respo...

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Detalles Bibliográficos
Autores principales: Falkeborn, Tina, Hinkula, Jorma, Olliver, Marie, Lindberg, Alf, Maltais, Anna-Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335733/
https://www.ncbi.nlm.nih.gov/pubmed/28253901
http://dx.doi.org/10.1186/s12985-017-0698-4