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Selections, frameshift mutations, and copy number variation detected on the surf(4.1) gene in the western Kenyan Plasmodium falciparum population

BACKGROUND: Plasmodium falciparum SURFIN(4.1) is a putative ligand expressed on the merozoite and likely on the infected red blood cell, whose gene was suggested to be under directional selection in the eastern Kenyan population, but under balancing selection in the Thai population. To understand th...

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Detalles Bibliográficos
Autores principales: Gitaka, Jesse N., Takeda, Mika, Kimura, Masatsugu, Idris, Zulkarnain Md, Chan, Chim W., Kongere, James, Yahata, Kazuhide, Muregi, Francis W., Ichinose, Yoshio, Kaneko, Akira, Kaneko, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335827/
https://www.ncbi.nlm.nih.gov/pubmed/28253868
http://dx.doi.org/10.1186/s12936-017-1743-x