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The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition
Mycobacterium tuberculosis is a facultative anaerobe and its characteristic pathological hallmark, the granuloma, exhibits hypoxia in humans and in most experimental models. Thus the host and bacillary adaptation to hypoxia is of central importance in understanding pathogenesis and thereby to derive...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335906/ https://www.ncbi.nlm.nih.gov/pubmed/27780773 http://dx.doi.org/10.1016/j.micinf.2016.10.001 |