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Early mutation bursts in colorectal tumors

Tumor growth is an evolutionary process involving accumulation of mutations, copy number alterations, and cancer stem cell (CSC) division and differentiation. As direct observation of this process is impossible, inference regarding when mutations occur and how stem cells divide is difficult. However...

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Detalles Bibliográficos
Autores principales: Zhao, Junsong, Salomon, Matthew P., Shibata, Darryl, Curtis, Christina, Siegmund, Kimberly, Marjoram, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336211/
https://www.ncbi.nlm.nih.gov/pubmed/28257429
http://dx.doi.org/10.1371/journal.pone.0172516