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Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells

Chronic lymphocytic leukemia (CLL) is associated with T cell dysfunction. Activated CLL cells are found within the lymphoid tumor micro-environment and overcoming immuno-suppression induced by these cells may improve anti-CLL immune responses. However, the mechanisms by which activated CLL cells inh...

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Detalles Bibliográficos
Autores principales: Hock, Barry D., MacPherson, Sean A., McKenzie, Judith L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336221/
https://www.ncbi.nlm.nih.gov/pubmed/28257435
http://dx.doi.org/10.1371/journal.pone.0172858