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Growth condition dependency is the major cause of non-responsiveness upon genetic perturbation

Investigating the role and interplay between individual proteins in biological processes is often performed by assessing the functional consequences of gene inactivation or removal. Depending on the sensitivity of the assay used for determining phenotype, between 66% (growth) and 53% (gene expressio...

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Detalles Bibliográficos
Autores principales: Amini, Saman, Holstege, Frank C. P., Kemmeren, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336285/
https://www.ncbi.nlm.nih.gov/pubmed/28257504
http://dx.doi.org/10.1371/journal.pone.0173432