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The thermodynamics of Pr55(Gag)-RNA interaction regulate the assembly of HIV

The interactions that occur during HIV Pr55(Gag) oligomerization and genomic RNA packaging are essential elements that facilitate HIV assembly. However, mechanistic details of these interactions are not clearly defined. Here, we overcome previous limitations in producing large quantities of full-len...

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Detalles Bibliográficos
Autores principales: Tanwar, Hanumant S., Khoo, Keith K., Garvey, Megan, Waddington, Lynne, Leis, Andrew, Hijnen, Marcel, Velkov, Tony, Dumsday, Geoff J., McKinstry, William J., Mak, Johnson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336307/
https://www.ncbi.nlm.nih.gov/pubmed/28222188
http://dx.doi.org/10.1371/journal.ppat.1006221