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Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis

BACKGROUND: Traumatic brain injury (TBI) is a complex disorder that is traditionally stratified based on clinical signs and symptoms. Recent imaging and molecular biomarker innovations provide unprecedented opportunities for improved TBI precision medicine, incorporating patho-anatomical and molecul...

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Detalles Bibliográficos
Autores principales: Nielson, Jessica L., Cooper, Shelly R., Yue, John K., Sorani, Marco D., Inoue, Tomoo, Yuh, Esther L., Mukherjee, Pratik, Petrossian, Tanya C., Paquette, Jesse, Lum, Pek Y., Carlsson, Gunnar E., Vassar, Mary J., Lingsma, Hester F., Gordon, Wayne A., Valadka, Alex B., Okonkwo, David O., Manley, Geoffrey T., Ferguson, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336356/
https://www.ncbi.nlm.nih.gov/pubmed/28257413
http://dx.doi.org/10.1371/journal.pone.0169490