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Folding behavior of a T-shaped, ribosome-binding translation enhancer implicated in a wide-spread conformational switch

Turnip crinkle virus contains a T-shaped, ribosome-binding, translation enhancer (TSS) in its 3’UTR that serves as a hub for interactions throughout the region. The viral RNA-dependent RNA polymerase (RdRp) causes the TSS/surrounding region to undergo a conformational shift postulated to inhibit tra...

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Detalles Bibliográficos
Autores principales: Le, My-Tra, Kasprzak, Wojciech K, Kim, Taejin, Gao, Feng, Young, Megan YL, Yuan, Xuefeng, Shapiro, Bruce A, Seog, Joonil, Simon, Anne E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336357/
https://www.ncbi.nlm.nih.gov/pubmed/28186489
http://dx.doi.org/10.7554/eLife.22883