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Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation
Membrane-integral pyrophosphatases (mPPases) couple the hydrolysis of pyrophosphate (PP(i)) to the pumping of Na(+), H(+), or both these ions across a membrane. Recently solved structures of the Na(+)-pumping Thermotoga maritima mPPase (TmPPase) and H(+)-pumping Vigna radiata mPPase revealed the bas...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Crystallographic Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336470/ https://www.ncbi.nlm.nih.gov/pubmed/28345008 http://dx.doi.org/10.1063/1.4978038 |