Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function

Inhibition of complement factor 5 (C5) reduced myocardial infarction in animal studies, while no benefit was found in clinical studies. Due to lack of cross-reactivity of clinically used C5 antibodies, different inhibitors were used in animal and clinical studies. Coversin (Ornithodoros moubata comp...

Descripción completa

Detalles Bibliográficos
Autores principales: Pischke, Soeren E., Gustavsen, A., Orrem, H. L., Egge, K. H., Courivaud, F., Fontenelle, H., Despont, A., Bongoni, A. K., Rieben, R., Tønnessen, T. I., Nunn, M. A., Scott, H., Skulstad, H., Barratt-Due, A., Mollnes, T. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336537/
https://www.ncbi.nlm.nih.gov/pubmed/28258298
http://dx.doi.org/10.1007/s00395-017-0610-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336537/
https://www.ncbi.nlm.nih.gov/pubmed/28258298
http://dx.doi.org/10.1007/s00395-017-0610-9

Ejemplares similares