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Bioequivalence Methodologies for Topical Drug Products: In Vitro and Ex Vivo Studies with a Corticosteroid and an Anti-Fungal Drug

OBJECTIVE: To examine whether in vitro and ex vivo measurements of topical drug product performance correlate with in vivo outcomes, such that more efficient experimental approaches can be reliably and reproducibly used to establish (in)equivalence between formulations for skin application. MATERIAL...

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Detalles Bibliográficos
Autores principales: Leal, Leila Bastos, Cordery, Sarah F., Delgado-Charro, M. Begoña, Bunge, Annette L., Guy, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336544/
https://www.ncbi.nlm.nih.gov/pubmed/28097506
http://dx.doi.org/10.1007/s11095-017-2099-1