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Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis

Hippo/YAP signaling is implicated in tumorigenesis and progression of various cancers. By inhibiting a plethora signaling cascades, resveratrol has strong anti-tumorigenic and anti-metastatic activity. In the present study, we demonstrate that resveratrol decreases the expression of YAP target genes...

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Detalles Bibliográficos
Autores principales: Kim, Yu Na, Choe, So Ra, Cho, Kyung Hwa, Cho, Do Yeun, Kang, Jaeku, Park, Chang Gyo, Lee, Hoi Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336560/
https://www.ncbi.nlm.nih.gov/pubmed/28232662
http://dx.doi.org/10.1038/emm.2016.151