Cargando…

Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis

Hippo/YAP signaling is implicated in tumorigenesis and progression of various cancers. By inhibiting a plethora signaling cascades, resveratrol has strong anti-tumorigenic and anti-metastatic activity. In the present study, we demonstrate that resveratrol decreases the expression of YAP target genes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Yu Na, Choe, So Ra, Cho, Kyung Hwa, Cho, Do Yeun, Kang, Jaeku, Park, Chang Gyo, Lee, Hoi Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336560/ https://www.ncbi.nlm.nih.gov/pubmed/28232662 http://dx.doi.org/10.1038/emm.2016.151

Ejemplares similares

RCP induces FAK phosphorylation and ovarian cancer cell invasion with inhibition by curcumin
por: Choe, So Ra, et al.
Publicado: (2018)

A RhoA–YAP–c-Myc signaling axis promotes the development of polycystic kidney disease
por: Cai, Jing, et al.
Publicado: (2018)

A YAP/TAZ–ARHGAP29–RhoA Signaling Axis Regulates Podocyte Protrusions and Integrin Adhesions
por: Rogg, Manuel, et al.
Publicado: (2023)

NPFFR2 Contributes to the Malignancy of Hepatocellular Carcinoma Development by Activating RhoA/YAP Signaling
por: Shin, Yuna, et al.
Publicado: (2022)

The Correlation between YAP and RhoA Expression in Prostate and Ovarian Tumor Stroma
por: Lee, Myung-Jin, et al.
Publicado: (2022)

RhoA/ROCK-YAP/TAZ Axis Regulates the Fibrotic Activity in Dexamethasone-Treated Human Trabecular Meshwork Cells
por: Liu, Zhicheng, et al.
Publicado: (2021)

Arhgap28 Is a RhoGAP that Inactivates RhoA and Downregulates Stress Fibers
por: Yeung, Ching-Yan Chloé, et al.
Publicado: (2014)

Cytoskeletal alteration modulates cancer cell invasion through RhoA-YAP signaling in stromal fibroblasts
por: Kim, Do Kyeong, et al.
Publicado: (2019)

Zeb1 for RCP-induced oral cancer cell invasion and its suppression by resveratrol
por: Kim, Jin Young, et al.
Publicado: (2020)

Androgens and NGF Mediate the Neurite-Outgrowth through Inactivation of RhoA
por: Di Donato, Marzia, et al.
Publicado: (2023)

Activation of the RhoA‐YAP‐β‐catenin signaling axis promotes the expansion of inner ear progenitor cells in 3D culture
por: Xia, Mingyu, et al.
Publicado: (2020)

RhoA enhances osteosarcoma resistance to MPPa-PDT via the Hippo/YAP signaling pathway
por: Zhan, Fangbiao, et al.
Publicado: (2021)

The mevalonate pathway promotes the metastasis of osteosarcoma by regulating YAP1 activity via RhoA
por: Du, Xing, et al.
Publicado: (2020)

p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer
por: Wen, Xiaoli, et al.
Publicado: (2020)

Inhibition of β1-AR/Gαs signaling promotes cardiomyocyte proliferation in juvenile mice through activation of RhoA-YAP axis
por: Sakabe, Masahide, et al.
Publicado: (2022)

Extracellular matrix stiffness mediates uterine repair via the Rap1a/ARHGAP35/RhoA/F-actin/YAP axis
por: Zhang, Tao, et al.
Publicado: (2023)

Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles
por: Shan, Shidong, et al.
Publicado: (2023)

RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal
por: Huang, Zongshun, et al.
Publicado: (2016)

The Short-Chain Fatty Acid Receptor GPR43 Modulates YAP/TAZ via RhoA
por: Park, Bi-Oh, et al.
Publicado: (2021)

JTE-013 Alleviates Pulmonary Fibrosis by Affecting the RhoA/YAP Pathway and Mitochondrial Fusion/Fission
por: Zhou, Jiaxu, et al.
Publicado: (2023)

Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
por: Zhang, Jason Z., et al.
Publicado: (2020)

RhoA improves cryopreservation of rooster sperm through the Rho/RhoA-associated kinase/cofilin pathway
por: Heng, Nuo, et al.
Publicado: (2022)

RhoA/Rho‐kinases in asthma: from pathogenesis to therapeutic targets
por: Zhang, Yan, et al.
Publicado: (2020)

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity
por: Yu, Olivia M, et al.
Publicado: (2018)

Integrin β3 overexpression contributes to podocyte injury through inhibiting RhoA/YAP signaling pathway
por: Li, Zhuo, et al.
Publicado: (2021)

SAR1A regulates the RhoA/YAP and autophagy signaling pathways to influence osteosarcoma invasion and metastasis
por: Zhan, Fangbiao, et al.
Publicado: (2022)

Breast cancer metastasis suppressor 1 (BRMS1) attenuates TGF-β1-induced breast cancer cell aggressiveness through downregulating HIF-1α expression
por: Cho, Kyung Hwa, et al.
Publicado: (2015)

RhoA/Rho kinase in spinal cord injury
por: Wu, Xiangbing, et al.
Publicado: (2016)

SEMA6A/RhoA/YAP axis mediates tumor-stroma interactions and prevents response to dual BRAF/MEK inhibition in BRAF-mutant melanoma
por: Loria, Rossella, et al.
Publicado: (2022)

RhoA suppresses pseudorabies virus replication in vitro
por: Li, Xin-Man, et al.
Publicado: (2023)

Lovastatin Inhibits RhoA to Suppress Canonical Wnt/β-Catenin Signaling and Alternative Wnt-YAP/TAZ Signaling in Colon Cancer
por: Xiao, Yi, et al.
Publicado: (2022)

Inactivating Mutations in GNA13 and RHOA in Burkitt’s Lymphoma and Diffuse Large B cell Lymphoma: A Tumor Suppressor Function for the Gα(13)/RhoA Axis in B Cells
por: O’Hayre, Morgan, et al.
Publicado: (2015)

Resveratrol enhances vascular reactivity in mice following lipopolysaccharide challenge via the RhoA-ROCK-MLCP pathway
por: Wang, Xu-Qing, et al.
Publicado: (2017)

RhoA‐ROCK competes with YAP to regulate amoeboid breast cancer cell migration in response to lymphatic‐like flow
por: Mohammadalipour, Amina, et al.
Publicado: (2022)

PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling
por: Chen, Hualin, et al.
Publicado: (2023)

RhoA controls furrow formation
por: Tuma, Rabiya S.
Publicado: (2005)

RhoA brings up the rear
por: Dove, Alan W.
Publicado: (2001)

Complementary receptors control RhoA
por: Robinson, Richard
Publicado: (2008)

RhoA Regulation of Cardiomyocyte Differentiation
por: Kaarbø, Mari, et al.
Publicado: (2013)

RhoA in aneurysmal subarachnoid hemorrhage
por: Ureña, Juan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_632panbis7ek1mevhrg6iimnm8