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miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene

BACKGROUND: Loss of CBX7 expression has been described in several malignant neoplasias, including human colon and thyroid carcinomas proposing CBX7 as a tumor suppressor gene with a key role in cancer progression. This role is supported from the development of benign and malignant neoplasias in Cbx7...

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Detalles Bibliográficos
Autores principales: Forzati, Floriana, De Martino, Marco, Esposito, Francesco, Sepe, Romina, Pellecchia, Simona, Malapelle, Umberto, Pellino, Gianluca, Arra, Claudio, Fusco, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336640/
https://www.ncbi.nlm.nih.gov/pubmed/28259135
http://dx.doi.org/10.1186/s12885-017-3158-z