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miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene
BACKGROUND: Loss of CBX7 expression has been described in several malignant neoplasias, including human colon and thyroid carcinomas proposing CBX7 as a tumor suppressor gene with a key role in cancer progression. This role is supported from the development of benign and malignant neoplasias in Cbx7...
Autores principales: | Forzati, Floriana, De Martino, Marco, Esposito, Francesco, Sepe, Romina, Pellecchia, Simona, Malapelle, Umberto, Pellino, Gianluca, Arra, Claudio, Fusco, Alfredo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336640/ https://www.ncbi.nlm.nih.gov/pubmed/28259135 http://dx.doi.org/10.1186/s12885-017-3158-z |
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