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Molecular genetics of microsatellite-unstable colorectal cancer for pathologists

BACKGROUND: Microsatellite-unstable colorectal cancers (CRC) that are due to deficient DNA mismatch repair (dMMR) represent approximately 15% of all CRCs in the United States. These microsatellite-unstable CRCs represent a heterogenous group of diseases with distinct oncogenesis pathways. There are...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Swanson, Benjamin J., Frankel, Wendy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336657/
https://www.ncbi.nlm.nih.gov/pubmed/28259170
http://dx.doi.org/10.1186/s13000-017-0613-8