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Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system

BACKGROUND: We present the first molecular characterization of glycerotoxin (GLTx), a potent neurotoxin found in the venom of the bloodworm Glycera tridactyla (Glyceridae, Annelida). Within the animal kingdom, GLTx shows a unique mode of action as it can specifically up-regulate the activity of Ca(v...

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Detalles Bibliográficos
Autores principales: Richter, Sandy, Helm, Conrad, Meunier, Frederic A., Hering, Lars, Campbell, Lahcen I., Drukewitz, Stephan H., Undheim, Eivind A. B., Jenner, Ronald A., Schiavo, Giampietro, Bleidorn, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336659/
https://www.ncbi.nlm.nih.gov/pubmed/28259138
http://dx.doi.org/10.1186/s12862-017-0904-4