Production of Human Cu,Zn SOD with Higher Activity and Lower Toxicity in E. coli via Mutation of Free Cysteine Residues

Although, as an antioxidant enzyme, human Cu,Zn superoxide dismutase 1 (hSOD1) can mitigate damage to cell components caused by free radicals generated by aerobic metabolism, large-scale manufacturing and clinical use of hSOD1 are still limited by the challenge of rapid and inexpensive production of...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Zhang, Yuejuan, Zi, Jing, Xue, Xiaochang, Wan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337334/
https://www.ncbi.nlm.nih.gov/pubmed/28299326
http://dx.doi.org/10.1155/2017/4817376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337334/
https://www.ncbi.nlm.nih.gov/pubmed/28299326
http://dx.doi.org/10.1155/2017/4817376

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