Predicting the Remaining Lifespan and Cultivation-Related Loss of Osteogenic Capacity of Bone Marrow Multipotential Stromal Cells Applicable across a Broad Donor Age Range

Background and Objectives. Culture expanded multipotential stromal cells (MSCs) have considerable potential for bone regeneration therapy but their wider use is constrained by the lack of simple and predictive assays of functional potency. Extended passaging leads to loss of multipotency but speed o...

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Detalles Bibliográficos
Autores principales: Churchman, Sarah M., Boxall, Sally A., McGonagle, Dennis, Jones, Elena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337353/
https://www.ncbi.nlm.nih.gov/pubmed/28298930
http://dx.doi.org/10.1155/2017/6129596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337353/
https://www.ncbi.nlm.nih.gov/pubmed/28298930
http://dx.doi.org/10.1155/2017/6129596

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