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Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis

Aurora kinase A (AURKA) has been implicated in the regulation of cell cycle progression, mitosis and a key number of oncogenic signaling pathways in various malignancies. However, little is known about its role in gastric cancer prognosis and genotoxic resistance. Here we found that AURKA was highly...

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Detalles Bibliográficos
Autores principales: Kamran, M, Long, Z-J, Xu, D, Lv, S-S, Liu, B, Wang, C-L, Xu, J, Lam, E W-F, Liu, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337621/
https://www.ncbi.nlm.nih.gov/pubmed/28218735
http://dx.doi.org/10.1038/oncsis.2016.80