Cargando…
Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis
Aurora kinase A (AURKA) has been implicated in the regulation of cell cycle progression, mitosis and a key number of oncogenic signaling pathways in various malignancies. However, little is known about its role in gastric cancer prognosis and genotoxic resistance. Here we found that AURKA was highly...
Autores principales: | Kamran, M, Long, Z-J, Xu, D, Lv, S-S, Liu, B, Wang, C-L, Xu, J, Lam, E W-F, Liu, Q |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337621/ https://www.ncbi.nlm.nih.gov/pubmed/28218735 http://dx.doi.org/10.1038/oncsis.2016.80 |
Ejemplares similares
-
Tension Sensing by Aurora B Kinase is Independent of Survivin-Based Centromere Localization
por: Campbell, Christopher S., et al.
Publicado: (2013) -
Activation of Aurora A kinase increases YAP stability via blockage of autophagy
por: Wang, Peng, et al.
Publicado: (2019) -
F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7
por: Liu, Y, et al.
Publicado: (2015) -
Epigenetic suppression of FBXL7 promotes metastasis
por: Moro, Loredana, et al.
Publicado: (2020) -
Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis
por: Chen, B B, et al.
Publicado: (2013)