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Fatty acid synthase regulates estrogen receptor-α signaling in breast cancer cells
Fatty acid synthase (FASN), the key enzyme for endogenous synthesis of fatty acids, is overexpressed and hyperactivated in a biologically aggressive subset of sex steroid-related tumors, including breast carcinomas. Using pharmacological and genetic approaches, we assessed the molecular relationship...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337623/ https://www.ncbi.nlm.nih.gov/pubmed/28240737 http://dx.doi.org/10.1038/oncsis.2017.4 |