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Beta-catenin Forms Protein Aggregation at High Concentrations in HEK293TCells

BACKGROUND: The canonical Wnt signal transduction (or the Wnt/β-catenin pathway) plays a crucial role in the development of animals and in carcinogenesis. Beta-catenin is the central component of this signaling pathway. The activation of Wnt/β-catenin signaling results in the cytoplasmic and nuclear...

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Detalles Bibliográficos
Autores principales: Jazi, Marie Saghaeian, Najafi, Seyed Mahmoud Arab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Journal of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337767/
https://www.ncbi.nlm.nih.gov/pubmed/28293052