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IFN-λ Inhibits Drug-Resistant HIV Infection of Macrophages

Type III interferons (IFN-λs) have been demonstrated to inhibit a number of viruses, including HIV. Here, we further examined the anti-HIV effect of IFN-λs in macrophages. We found that IFN-λs synergistically enhanced anti-HIV activity of antiretrovirals [azidothymidine (AZT), efavirenz, indinavir,...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Wang, He, Liu, Man-Qing, Li, Jie-Liang, Zhou, Run-Hong, Zhou, Yu, Wang, Yi-Zhong, Zhou, Wang, Ho, Wen-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337814/
https://www.ncbi.nlm.nih.gov/pubmed/28321215
http://dx.doi.org/10.3389/fimmu.2017.00210