Sildenafil Can Affect Innate and Adaptive Immune System in Both Experimental Animals and Patients

Sildenafil, a type 5 phosphodiesterase inhibitor (PDE5-I), is primarily used for treating erectile dysfunction. Sildenafil inhibits the degradation of cyclic guanosine monophosphate (cGMP) by competing with cGMP for binding site of PDE5. cGMP is a secondary messenger activating protein kinases and a...

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Detalles Bibliográficos
Autores principales: Kniotek, Monika, Boguska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337856/
https://www.ncbi.nlm.nih.gov/pubmed/28316997
http://dx.doi.org/10.1155/2017/4541958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337856/
https://www.ncbi.nlm.nih.gov/pubmed/28316997
http://dx.doi.org/10.1155/2017/4541958

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