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Sildenafil Can Affect Innate and Adaptive Immune System in Both Experimental Animals and Patients

Sildenafil, a type 5 phosphodiesterase inhibitor (PDE5-I), is primarily used for treating erectile dysfunction. Sildenafil inhibits the degradation of cyclic guanosine monophosphate (cGMP) by competing with cGMP for binding site of PDE5. cGMP is a secondary messenger activating protein kinases and a...

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Detalles Bibliográficos
Autores principales:	Kniotek, Monika, Boguska, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2017
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337856/ https://www.ncbi.nlm.nih.gov/pubmed/28316997 http://dx.doi.org/10.1155/2017/4541958

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