Identifying the receptor subtype selectivity of retinoid X and retinoic acid receptors via quantum mechanics

Understanding and identifying the receptor subtype selectivity of a ligand is an important issue in the field of drug discovery. Using a combination of classical molecular mechanics and quantum mechanical calculations, this report assesses the receptor subtype selectivity for the human retinoid X re...

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Detalles Bibliográficos
Autores principales: Tsuji, Motonori, Shudo, Koichi, Kagechika, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337894/
https://www.ncbi.nlm.nih.gov/pubmed/28286734
http://dx.doi.org/10.1002/2211-5463.12188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337894/
https://www.ncbi.nlm.nih.gov/pubmed/28286734
http://dx.doi.org/10.1002/2211-5463.12188

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