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Mitotic phosphorylation of CCCTC‐binding factor (CTCF) reduces its DNA binding activity

During mitosis, higher order chromatin structures are disrupted and chromosomes are condensed to achieve accurate chromosome segregation. CCCTC‐binding factor (CTCF) is a highly conserved and ubiquitously expressed C2H2‐type zinc finger protein which is considered to be involved in epigenetic memory...

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Detalles Bibliográficos
Autores principales: Sekiya, Takeshi, Murano, Kensaku, Kato, Kohsuke, Kawaguchi, Atsushi, Nagata, Kyosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337899/
https://www.ncbi.nlm.nih.gov/pubmed/28286735
http://dx.doi.org/10.1002/2211-5463.12189