Inhibition of Interleukin-17A, But Not Interleukin-17F, Signaling Lowers Blood Pressure, and Reduces End-Organ Inflammation in Angiotensin II–Induced Hypertension

Inflammatory cytokines play a major role in the pathophysiology of hypertension. The authors previously showed that genetic deletion of interleukin (IL)-17A results in blunted hypertension and reduced renal/vascular dysfunction. With the emergence of a new class of monoclonal antibody–based drugs fo...

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Detalles Bibliográficos
Autores principales: Saleh, Mohamed A., Norlander, Allison E., Madhur, Meena S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
PRECLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337944/
https://www.ncbi.nlm.nih.gov/pubmed/28280792
http://dx.doi.org/10.1016/j.jacbts.2016.07.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337944/
https://www.ncbi.nlm.nih.gov/pubmed/28280792
http://dx.doi.org/10.1016/j.jacbts.2016.07.009

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