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Evolution of complexity in the zebrafish synapse proteome

The proteome of human brain synapses is highly complex and is mutated in over 130 diseases. This complexity arose from two whole-genome duplications early in the vertebrate lineage. Zebrafish are used in modelling human diseases; however, its synapse proteome is uncharacterized, and whether the tele...

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Detalles Bibliográficos
Autores principales: Bayés, Àlex, Collins, Mark O., Reig-Viader, Rita, Gou, Gemma, Goulding, David, Izquierdo, Abril, Choudhary, Jyoti S., Emes, Richard D., Grant, Seth G. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337974/
https://www.ncbi.nlm.nih.gov/pubmed/28252024
http://dx.doi.org/10.1038/ncomms14613