Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions

Voltage-gated Kv1.3 and Ca(2+)-dependent KCa3.1 are the most prevalent K(+) channels expressed by human and rat T cells. Despite the preferential upregulation of Kv1.3 over KCa3.1 on autoantigen-experienced effector memory T cells, whether Kv1.3 is required for their induction and function is unclea...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiang, Eugene Y., Li, Tianbo, Jeet, Surinder, Peng, Ivan, Zhang, Juan, Lee, Wyne P., DeVoss, Jason, Caplazi, Patrick, Chen, Jun, Warming, Søren, Hackos, David H., Mukund, Susmith, Koth, Christopher M., Grogan, Jane L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337993/
https://www.ncbi.nlm.nih.gov/pubmed/28248292
http://dx.doi.org/10.1038/ncomms14644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337993/
https://www.ncbi.nlm.nih.gov/pubmed/28248292
http://dx.doi.org/10.1038/ncomms14644

Ejemplares similares