Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

γδ T cells are considered to be innate-like lymphocytes that respond rapidly to stress without clonal selection and differentiation. Here we use next-generation sequencing to probe how this paradigm relates to human Vδ2(neg) T cells, implicated in responses to viral infection and cancer. The prevale...

Descripción completa

Detalles Bibliográficos
Autores principales: Davey, Martin S., Willcox, Carrie R., Joyce, Stephen P., Ladell, Kristin, Kasatskaya, Sofya A., McLaren, James E., Hunter, Stuart, Salim, Mahboob, Mohammed, Fiyaz, Price, David A., Chudakov, Dmitriy M., Willcox, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337994/
https://www.ncbi.nlm.nih.gov/pubmed/28248310
http://dx.doi.org/10.1038/ncomms14760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337994/
https://www.ncbi.nlm.nih.gov/pubmed/28248310
http://dx.doi.org/10.1038/ncomms14760

Ejemplares similares