Fluorescence Self-Quenching from Reporter Dyes Informs on the Structural Properties of Amyloid Clusters Formed in Vitro and in Cells

[Image: see text] The characterization of the aggregation kinetics of protein amyloids and the structural properties of the ensuing aggregates are vital in the study of the pathogenesis of many neurodegenerative diseases and the discovery of therapeutic targets. In this article, we show that the flu...

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Detalles Bibliográficos
Autores principales: Chen, WeiYue, Young, Laurence J., Lu, Meng, Zaccone, Alessio, Ströhl, Florian, Yu, Na, Kaminski Schierle, Gabriele S., Kaminski, Clemens F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338000/
https://www.ncbi.nlm.nih.gov/pubmed/28073262
http://dx.doi.org/10.1021/acs.nanolett.6b03686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338000/
https://www.ncbi.nlm.nih.gov/pubmed/28073262
http://dx.doi.org/10.1021/acs.nanolett.6b03686

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