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A 3D self-organizing multicellular epidermis model of barrier formation and hydration with realistic cell morphology based on EPISIM
The epidermis and the stratum corneum (SC) as its outermost layer have evolved to protect the body from evaporative water loss to the environment. To morphologically represent the extremely flattened cells of the SC - and thereby the epidermal barrier - in a multicellular computational model, we dev...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338006/ https://www.ncbi.nlm.nih.gov/pubmed/28262741 http://dx.doi.org/10.1038/srep43472 |