Cargando…

Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain

It is well known that mutations in the gene coding for amyloid precursor protein are responsible for autosomal dominant forms of Alzheimer’s disease. Proteolytic processing of the protein leads to a number of metabolites including the amyloid beta peptide. Although brain amyloid precursor protein ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Puig, Kendra L., Brose, Stephen A., Zhou, Xudong, Sens, Mary A., Combs, Gerald F., Jensen, Michael D., Golovko, Mikhail Y., Combs, Colin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338020/
https://www.ncbi.nlm.nih.gov/pubmed/28262782
http://dx.doi.org/10.1038/srep43725