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Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules

Endothelial exocytosis of Weibel–Palade body (WPB) is one of the first lines of defence against vascular injury. However, the mechanisms that control WPB exocytosis in the final stages (including the docking, priming and fusion of granules) are poorly understood. Here we show that the focal adhesion...

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Detalles Bibliográficos
Autores principales: Han, Xiaofan, Li, Pin, Yang, Zhenghao, Huang, Xiaoshuai, Wei, Guoqin, Sun, Yujie, Kang, Xuya, Hu, Xueting, Deng, Qiuping, Chen, Liangyi, He, Aibin, Huo, Yingqing, Li, Dong, Betzig, Eric, Luo, Jincai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338022/
https://www.ncbi.nlm.nih.gov/pubmed/28256511
http://dx.doi.org/10.1038/ncomms14639