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Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules
Endothelial exocytosis of Weibel–Palade body (WPB) is one of the first lines of defence against vascular injury. However, the mechanisms that control WPB exocytosis in the final stages (including the docking, priming and fusion of granules) are poorly understood. Here we show that the focal adhesion...
Autores principales: | Han, Xiaofan, Li, Pin, Yang, Zhenghao, Huang, Xiaoshuai, Wei, Guoqin, Sun, Yujie, Kang, Xuya, Hu, Xueting, Deng, Qiuping, Chen, Liangyi, He, Aibin, Huo, Yingqing, Li, Dong, Betzig, Eric, Luo, Jincai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338022/ https://www.ncbi.nlm.nih.gov/pubmed/28256511 http://dx.doi.org/10.1038/ncomms14639 |
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