D-form KLKLLLLLKLK-NH(2) peptide exerts higher antimicrobial properties than its L-form counterpart via an association with bacterial cell wall components

The antimicrobial peptide KLKLLLLLKLK-NH(2) was developed based on sapesin B, and synthesized using D-amino acids. Biochemical properties of the D-form and L-form KLKLLLLLKLK-NH(2) peptides were compared. In order to limit the effects due to bacterial resistance to proteolysis, antimicrobial activit...

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Detalles Bibliográficos
Autores principales: Manabe, Takayuki, Kawasaki, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338256/
https://www.ncbi.nlm.nih.gov/pubmed/28262682
http://dx.doi.org/10.1038/srep43384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338256/
https://www.ncbi.nlm.nih.gov/pubmed/28262682
http://dx.doi.org/10.1038/srep43384

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