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High glucose levels boost the aggressiveness of highly metastatic cholangiocarcinoma cells via O-GlcNAcylation

Increased glucose utilization is a feature of cancer cells to support cell survival, proliferation, and metastasis. An association between diabetes mellitus and cancer progression was previously demonstrated in cancers including cholangiocarcinoma (CCA). This study was aimed to determine the effects...

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Detalles Bibliográficos
Autores principales: Phoomak, Chatchai, Vaeteewoottacharn, Kulthida, Silsirivanit, Atit, Saengboonmee, Charupong, Seubwai, Wunchana, Sawanyawisuth, Kanlayanee, Wongkham, Chaisiri, Wongkham, Sopit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338328/
https://www.ncbi.nlm.nih.gov/pubmed/28262738
http://dx.doi.org/10.1038/srep43842