Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation

The role of mesenchymal stromal cells (MSCs) in the pathogenesis of myelodysplastic syndromes (MDS) has been increasingly addressed, but has yet to be clearly elucidated. In this investigation, we found that MDS cells proliferated to a greater extent on MDS-derived MSCs compared to normal MSCs. Matr...

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Detalles Bibliográficos
Autores principales: Zhao, Sida, Zhao, Youshan, Guo, Juan, Fei, Chengming, Zheng, Qingqing, Li, Xiao, Chang, Chunkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338350/
https://www.ncbi.nlm.nih.gov/pubmed/28262842
http://dx.doi.org/10.1038/srep43849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338350/
https://www.ncbi.nlm.nih.gov/pubmed/28262842
http://dx.doi.org/10.1038/srep43849

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